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5CEZ

Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with an early putative precursor of the PGT121 family at 3.0 Angstrom

Summary for 5CEZ
Entry DOI10.2210/pdb5cez/pdb
Related5CEX 5CEY
DescriptorEnvelope glycoprotein gp160, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (14 entities in total)
Functional Keywordshiv-1, antibody, immune system, viral protein-immune system complex, viral protein/immune system
Biological sourceHuman immunodeficiency virus 1
More
Total number of polymer chains6
Total formula weight178725.86
Authors
Wilson, I.A.,Garces, F. (deposition date: 2015-07-08, release date: 2015-12-23, Last modification date: 2023-09-27)
Primary citationGarces, F.,Lee, J.H.,de Val, N.,Torrents de la Pena, A.,Kong, L.,Puchades, C.,Hua, Y.,Stanfield, R.L.,Burton, D.R.,Moore, J.P.,Sanders, R.W.,Ward, A.B.,Wilson, I.A.
Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43:1053-1063, 2015
Cited by
PubMed: 26682982
DOI: 10.1016/j.immuni.2015.11.007
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.031 Å)
Structure validation

217705

數據於2024-03-27公開中

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