5CEX

Crystal Structure of Fab 32H+109L, a putative precursor of the PGT121 family of potent HIV-1 antibodies

Summary for 5CEX

Entry DOI	10.2210/pdb5cex/pdb
Related	5CEY 5CEZ
Descriptor	Antibody 9H+3L Fab light chain, Antibody 9H+3L Fab heavy chain, TETRAETHYLENE GLYCOL, ... (7 entities in total)
Functional Keywords	hiv-1, immune system, antibody
Biological source	Homo sapiens More
Total number of polymer chains	4
Total formula weight	99166.38
Authors	Garces, F.,Wilson, I.A. (deposition date: 2015-07-07, release date: 2015-12-23, Last modification date: 2023-09-27)
Primary citation	Garces, F.,Lee, J.H.,de Val, N.,Torrents de la Pena, A.,Kong, L.,Puchades, C.,Hua, Y.,Stanfield, R.L.,Burton, D.R.,Moore, J.P.,Sanders, R.W.,Ward, A.B.,Wilson, I.A. Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans. Immunity, 43:1053-1063, 2015 Cited by PubMed: 26682982 DOI: 10.1016/j.immuni.2015.11.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.105 Å)

Structure validation