5CB7

Crystallographic structure of human rotavirus K8 VP8* in complex with A-type HBGA

Summary for 5CB7

• Entry DOI: 10.2210/pdb5cb7/pdb
• Descriptor: Outer capsid protein VP4, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]alpha-D-galactopyranose, 2-acetamido-2-deoxy-alpha-D-galactopyranose, ... (8 entities in total)
• Functional Keywords: carbohydrate-recognizing protein, lectin, rotavirus, vp8*, viral protein, sugar binding protein
• Biological source: Rotavirus A (strain Human/Japan/K8/1977 G1-P3A[9]-Ix-Rx-Cx-Mx-A1-Nx-Tx-Ex-H3) (RV-A)
• Total number of polymer chains: 2
• Total formula weight: 38638.26

Authors

Yu, X.,Blanchard, H. (deposition date: 2015-06-30, release date: 2016-06-08, Last modification date: 2024-03-06)

• Primary citation: Yu, X.,Mishra, R.,Holloway, G.,von Itzstein, M.,Coulson, B.S.,Blanchard, H.; Substantial Receptor-induced Structural Rearrangement of Rotavirus VP8*: Potential Implications for Cross-Species Infection.; Chembiochem, 16:2176-2181, 2015; PubMed: 26250751; DOI: 10.1002/cbic.201500360

Experimental method

X-RAY DIFFRACTION (1.35 Å)