5C8S
Crystal structure of the SARS coronavirus nsp14-nsp10 complex with functional ligands SAH and GpppA
5C8S の概要
エントリーDOI | 10.2210/pdb5c8s/pdb |
関連するPDBエントリー | 5C8T 5C8U |
分子名称 | Non-structural protein 10, Guanine-N7 methyltransferase, ZINC ION, ... (6 entities in total) |
機能のキーワード | nsp14, nsp10, exoribonuclease, methyltransferase, transferase |
由来する生物種 | Human SARS coronavirus (SARS-CoV) 詳細 |
細胞内の位置 | Papain-like proteinase: Host membrane; Multi-pass membrane protein. Non-structural protein 4: Host membrane; Multi-pass membrane protein. Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region . Helicase: Host endoplasmic reticulum-Golgi intermediate compartment . Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region : P0C6X7 P0C6X7 |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 153488.05 |
構造登録者 | |
主引用文献 | Ma, Y.Y.,Wu, L.J.,Shaw, N.,Gao, Y.,Wang, J.,Sun, Y.N.,Lou, Z.Y.,Yan, L.M.,Zhang, R.G.,Rao, Z.H. Structural basis and functional analysis of the SARS coronavirus nsp14-nsp10 complex Proc.Natl.Acad.Sci.USA, 112:9436-9441, 2015 Cited by PubMed: 26159422DOI: 10.1073/pnas.1508686112 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (3.326 Å) |
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