Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5C8I

Joint X-ray/neutron structure of Human Carbonic Anhydrase II in complex with Methazolamide

Summary for 5C8I
Entry DOI10.2210/pdb5c8i/pdb
Related4G0C
DescriptorCarbonic anhydrase 2, ZINC ION, N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide, ... (4 entities in total)
Functional Keywordsmethazolamide, acetazolamide, water displacement, lyase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight29590.74
Authors
Aggarwal, M.,Kovalevsky, A.Y.,Fisher, S.Z.,McKenna, R. (deposition date: 2015-06-25, release date: 2016-07-20, Last modification date: 2024-03-06)
Primary citationAggarwal, M.,Kovalevsky, A.Y.,Velazquez, H.,Fisher, S.Z.,Smith, J.C.,McKenna, R.
Neutron structure of human carbonic anhydrase II in complex with methazolamide: mapping the solvent and hydrogen-bonding patterns of an effective clinical drug.
IUCrJ, 3:319-325, 2016
Cited by
PubMed: 28461893
DOI: 10.1107/S2052252516010514
PDB entries with the same primary citation
Experimental method
NEUTRON DIFFRACTION (2.2 Å)
X-RAY DIFFRACTION (1.56 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon