5C36

Crystal structure of GTA + UDP-C-Gal + DI

5C36 の概要

• エントリーDOI: 10.2210/pdb5c36/pdb
• 関連するPDBエントリー: 5BXC 5C1G 5C1H 5C1L 5C38 5C3A 5C3B 5C3D 5C47 5C48 5C49 5C4B 5C4C 5C4D 5C4E 5C4F 5C8R
• 分子名称: Histo-blood group ABO system transferase, MANGANESE (II) ION, octyl 3-deoxy-2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-xylo-hexopyranoside, ... (5 entities in total)
• 機能のキーワード: glycosyltransferase deoxyinhibitor abo(h) blood-group system complex, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35575.62

構造登録者

Gagnon, S.,Meloncelli, P.,Zheng, R.B.,Haji-Ghassemi, O.,Johal, A.R.,Borisova, S.N.,Lowary, T.L.,Evans, S.V. (登録日: 2015-06-17, 公開日: 2015-09-23, 最終更新日: 2023-09-27)

• 主引用文献: Gagnon, S.M.,Meloncelli, P.J.,Zheng, R.B.,Haji-Ghassemi, O.,Johal, A.R.,Borisova, S.N.,Lowary, T.L.,Evans, S.V.; High Resolution Structures of the Human ABO(H) Blood Group Enzymes in Complex with Donor Analogs Reveal That the Enzymes Utilize Multiple Donor Conformations to Bind Substrates in a Stepwise Manner.; J.Biol.Chem., 290:27040-27052, 2015; PubMed: 26374898; DOI: 10.1074/jbc.M115.682401

実験手法

X-RAY DIFFRACTION (1.55 Å)