5BYJ

Schistosoma mansoni (Blood Fluke) Sulfotransferase/R-oxamniquine Complex

Summary for 5BYJ

• Entry DOI: 10.2210/pdb5byj/pdb
• Related: 5BYK
• Descriptor: Sulfotransferase, ADENOSINE-3'-5'-DIPHOSPHATE, {(2R)-7-nitro-2-[(propan-2-ylamino)methyl]-1,2,3,4-tetrahydroquinolin-6-yl}methanol, ... (4 entities in total)
• Functional Keywords: sulfotransferase, parasite, oxamniquine, drug resistance, transferase
• Biological source: Schistosoma mansoni (Blood fluke)
• Total number of polymer chains: 1
• Total formula weight: 30683.10

Authors

Taylor, A.B.,Cao, X.,Holloway, S.P.,Hart, P.J. (deposition date: 2015-06-10, release date: 2015-09-30, Last modification date: 2023-09-27)

• Primary citation: Taylor, A.B.,Pica-Mattoccia, L.,Polcaro, C.M.,Donati, E.,Cao, X.,Basso, A.,Guidi, A.,Rugel, A.R.,Holloway, S.P.,Anderson, T.J.,Hart, P.J.,Cioli, D.,LoVerde, P.T.; Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine.; Plos Negl Trop Dis, 9:e0004132-e0004132, 2015; PubMed: 26485649; DOI: 10.1371/journal.pntd.0004132

Experimental method

X-RAY DIFFRACTION (1.8 Å)