5BXJ
Complex of the Fk1 domain mutant A19T of FKBP51 with 4-Nitrophenol
Summary for 5BXJ
Entry DOI | 10.2210/pdb5bxj/pdb |
Descriptor | Peptidyl-prolyl cis-trans isomerase FKBP5, P-NITROPHENOL (3 entities in total) |
Functional Keywords | cochaperone, fk506, 4-nitrophenol, isomerase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: Q13451 |
Total number of polymer chains | 1 |
Total formula weight | 14296.38 |
Authors | |
Primary citation | Wu, D.,Tao, X.,Chen, Z.P.,Han, J.T.,Jia, W.J.,Zhu, N.,Li, X.,Wang, Z.,He, Y.X. The environmental endocrine disruptor p-nitrophenol interacts with FKBP51, a positive regulator of androgen receptor and inhibits androgen receptor signaling in human cells J. Hazard. Mater., 307:193-201, 2016 Cited by PubMed: 26780698DOI: 10.1016/j.jhazmat.2015.12.045 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.24 Å) |
Structure validation
Download full validation report