5BX6

PKA in complex with a halogenated phthalazinone fragment compound.

5BX6 の概要

• エントリーDOI: 10.2210/pdb5bx6/pdb
• 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, 4-chlorophthalazin-1(2H)-one, ... (5 entities in total)
• 機能のキーワード: inhibitor, protein kinase, structure-guided, fragment-based, transferase
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cytoplasm. Isoform 2: Cell projection, cilium, flagellum: P17612
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43650.07

構造登録者

Narayanan, D.,Alam, K.A.,Engh, R.A. (登録日: 2015-06-08, 公開日: 2016-09-14, 最終更新日: 2024-01-10)

• 主引用文献: Narayanan, D.,Gani, O.A.,Alam, K.A.,Engh, R.A.; PKA based studies of ligand interactions with a methionine gatekeeper.; To Be Published,

実験手法

X-RAY DIFFRACTION (1.89 Å)