5BSI
Crystal structure of Y36A mutant of human macrophage migration inhibitory factor
Summary for 5BSI
Entry DOI | 10.2210/pdb5bsi/pdb |
Related | 5BS9 5BSC 5BSJ |
Descriptor | Macrophage migration inhibitory factor, SULFATE ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | isomerase, surface, mutation |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: P14174 |
Total number of polymer chains | 8 |
Total formula weight | 99424.74 |
Authors | Pantouris, G.,Lolis, E. (deposition date: 2015-06-02, release date: 2015-09-30, Last modification date: 2023-09-27) |
Primary citation | Pantouris, G.,Syed, M.A.,Fan, C.,Rajasekaran, D.,Cho, T.Y.,Rosenberg, E.M.,Bucala, R.,Bhandari, V.,Lolis, E.J. An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22:1197-1205, 2015 Cited by PubMed: 26364929DOI: 10.1016/j.chembiol.2015.08.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)