5BSI

Crystal structure of Y36A mutant of human macrophage migration inhibitory factor

Summary for 5BSI

• Entry DOI: 10.2210/pdb5bsi/pdb
• Related: 5BS9 5BSC 5BSJ
• Descriptor: Macrophage migration inhibitory factor, SULFATE ION, GLYCEROL, ... (4 entities in total)
• Functional Keywords: isomerase, surface, mutation
• Biological source: Homo sapiens (Human)
• Cellular location: Secreted: P14174
• Total number of polymer chains: 8
• Total formula weight: 99424.74

Authors

Pantouris, G.,Lolis, E. (deposition date: 2015-06-02, release date: 2015-09-30, Last modification date: 2023-09-27)

• Primary citation: Pantouris, G.,Syed, M.A.,Fan, C.,Rajasekaran, D.,Cho, T.Y.,Rosenberg, E.M.,Bucala, R.,Bhandari, V.,Lolis, E.J.; An Analysis of MIF Structural Features that Control Functional Activation of CD74.; Chem.Biol., 22:1197-1205, 2015; PubMed: 26364929; DOI: 10.1016/j.chembiol.2015.08.006

Experimental method

X-RAY DIFFRACTION (2 Å)