5BSI
Crystal structure of Y36A mutant of human macrophage migration inhibitory factor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Macrophage migration inhibitory factor | polymer | 114 | 12263.0 | 8 | UniProt (P14174) Pfam (PF01187) | Homo sapiens (Human) | MIF, Glycosylation-inhibiting factor, GIF, L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase |
| 2 | I, K, M, O, R... (A, B, C, D, E...) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 3 | J, L, N, P, Q... (A, B, C, D, F) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 4 | AA, BA, CA, DA, W... (E, F, G, J, A...) | water | water | 18.0 | 576 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, J: 1 - 114 (UniProt: P14174)
| PDB | External Database | Details |
|---|---|---|
| Ala 36 | Tyr 37 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 98103.7 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1321.1 | |
| All* | Total formula weight | 99424.7 |
