5BQX
Crystal structure of human STING in complex with 3'2'-cGAMP
Summary for 5BQX
Entry DOI | 10.2210/pdb5bqx/pdb |
Related | 4KSY |
Descriptor | Stimulator of interferon genes protein, 3'2'-cGAMP (3 entities in total) |
Functional Keywords | sting, 3'2'-cgamp, immune system |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 27855.06 |
Authors | Wu, J.,Zhang, X.,Chen, Z.J.,Chen, C. (deposition date: 2015-05-29, release date: 2015-06-24, Last modification date: 2024-03-06) |
Primary citation | Shi, H.,Wu, J.,Chen, Z.J.,Chen, C. Molecular basis for the specific recognition of the metazoan cyclic GMP-AMP by the innate immune adaptor protein STING. Proc.Natl.Acad.Sci.USA, 112:8947-8952, 2015 Cited by PubMed: 26150511DOI: 10.1073/pnas.1507317112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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