5BQM

Crystal structure of SXN101959, a Clostridium botulinum neurotoxin type D derivative and targeted secretion inhibitor

5BQM の概要

• エントリーDOI: 10.2210/pdb5bqm/pdb
• 分子名称: Botulinum neurotoxin type D, Somatoliberin,Botulinum neurotoxin type D, ZINC ION, ... (4 entities in total)
• 機能のキーワード: botulinum neurotoxin, targeted secretion inhibitors, endopeptidase, type d, protein engineering, hydrolase
• 由来する生物種: Clostridium botulinum; 詳細
• 細胞内の位置: Botulinum neurotoxin D light chain: Secreted. Botulinum neurotoxin D heavy chain: Secreted: P19321 P19321
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 210922.22

構造登録者

Masuyer, G.,Davies, J.R.,Moore, K.,Chaddock, J.A.,Acharya, K.R. (登録日: 2015-05-29, 公開日: 2015-08-19, 最終更新日: 2024-01-10)

• 主引用文献: Masuyer, G.,Davies, J.R.,Moore, K.,Chaddock, J.A.,Ravi Acharya, K.; Structural analysis of Clostridium botulinum neurotoxin type D as a platform for the development of targeted secretion inhibitors.; Sci Rep, 5:13397-13397, 2015; PubMed: 26324071; DOI: 10.1038/srep13397

実験手法

X-RAY DIFFRACTION (3.1 Å)