5BNQ

Crystal structure of hRANKL-mRANK complex

5BNQ の概要

• エントリーDOI: 10.2210/pdb5bnq/pdb
• 分子名称: Tumor necrosis factor ligand superfamily member 11, Tumor necrosis factor receptor superfamily member 11A, PHOSPHATE ION, ... (6 entities in total)
• 機能のキーワード: rank, rankl, rankl-rank complex, tnfsf11, tnfrsf11a, tnf superfamily, cytokine
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Isoform 1: Cell membrane; Single-pass type II membrane protein. Isoform 3: Cell membrane; Single-pass type II membrane protein. Isoform 2: Cytoplasm . Tumor necrosis factor ligand superfamily member 11, soluble form: Secreted : O14788; Cell membrane ; Single-pass type I membrane protein : O35305
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 42758.80

構造登録者

Ren, J. (登録日: 2015-05-26, 公開日: 2015-10-14, 最終更新日: 2024-01-10)

• 主引用文献: Liu, C.,Zhao, Y.,He, W.,Wang, W.,Chen, Y.,Zhang, S.,Ma, Y.,Gohda, J.,Ishida, T.,Walter, T.S.,Owens, R.J.,Stuart, D.I.,Ren, J.,Gao, B.; A RANKL mutant used as an inter-species vaccine for efficient immunotherapy of osteoporosis.; Sci Rep, 5:14150-14150, 2015; PubMed: 26412210; DOI: 10.1038/srep14150

実験手法

X-RAY DIFFRACTION (2.8 Å)