5BNL
Deciphering the Mechanism of Carbonic Anhydrase Inhibition with Coumarins and Thiocoumarins
Summary for 5BNL
Entry DOI | 10.2210/pdb5bnl/pdb |
Related | 3F8E |
Descriptor | Carbonic anhydrase 2, ZINC ION, MERCURY (II) ION, ... (5 entities in total) |
Functional Keywords | hca2, coumarin, inhibitors, lyase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29362.80 |
Authors | Temperini, C.,Maresca, A.,Pochet, L.,Masereel, B.,Scozzafava, A.,Supuran, C.T. (deposition date: 2015-05-26, release date: 2015-07-15, Last modification date: 2024-01-10) |
Primary citation | Maresca, A.,Temperini, C.,Pochet, L.,Masereel, B.,Scozzafava, A.,Supuran, C.T. Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins. J.Med.Chem., 53:335-344, 2010 Cited by PubMed: 19911821DOI: 10.1021/jm901287j PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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