5B55

Crystal structure of hydrogen sulfide-producing enzyme (Fn1055) D232N mutant in complexed with alpha-aminoacrylate intermediate: lysine-dimethylated form

5B55 の概要

• エントリーDOI: 10.2210/pdb5b55/pdb
• 関連するPDBエントリー: 5B53 5B54
• 分子名称: Cysteine synthase, PYRIDOXAL-5'-PHOSPHATE, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, ... (5 entities in total)
• 機能のキーワード: pyridoxal 5'-phosphate dependent enzyme, alpha-aminoacrylate, transferase
• 由来する生物種: Fusobacterium nucleatum subsp. nucleatum strain ATCC 25586
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 78467.16

構造登録者

Kezuka, Y.,Yoshida, Y.,Nonaka, T. (登録日: 2016-04-22, 公開日: 2017-04-26, 最終更新日: 2023-11-08)

• 主引用文献: Kezuka, Y.,Ishida, T.,Yoshida, Y.,Nonaka, T.; Structural insights into the catalytic mechanism of cysteine (hydroxyl) lyase from the hydrogen sulfide-producing oral pathogen,Fusobacterium nucleatum.; Biochem. J., 475:733-748, 2018; PubMed: 29343611; DOI: 10.1042/BCJ20170838

実験手法

X-RAY DIFFRACTION (2.14 Å)