5AZ5
Crystal structure of human TLR8 in complex with MB-343
Summary for 5AZ5
Entry DOI | 10.2210/pdb5az5/pdb |
Descriptor | Toll-like receptor 8, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | immune system, tlr8, adjuvant, vaccine adjuvants, innate immunity, glycosylation, viral infection, tlr |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 382394.16 |
Authors | Tanji, H.,Ohto, U.,Shimizu, T. (deposition date: 2015-09-27, release date: 2016-10-05, Last modification date: 2020-07-29) |
Primary citation | Tanji, H.,Ohto, U.,Shimizu, T. Crystal structure of human TLR8 in complex with MB-343 To Be Published, |
Experimental method |
Structure validation
Download full validation report