5AZ5

Crystal structure of human TLR8 in complex with MB-343

5AZ5 の概要

• エントリーDOI: 10.2210/pdb5az5/pdb
• 分子名称: Toll-like receptor 8, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: immune system, tlr8, adjuvant, vaccine adjuvants, innate immunity, glycosylation, viral infection, tlr
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 382394.16

構造登録者

Tanji, H.,Ohto, U.,Shimizu, T. (登録日: 2015-09-27, 公開日: 2016-10-05, 最終更新日: 2020-07-29)

• 主引用文献: Tanji, H.,Ohto, U.,Shimizu, T.; Crystal structure of human TLR8 in complex with MB-343; To Be Published,

実験手法

X-RAY DIFFRACTION (2.4 Å)