5AYR
The crystal structure of SAUGI/human UDG complex
Summary for 5AYR
Entry DOI | 10.2210/pdb5ayr/pdb |
Related | 5AYS |
Descriptor | Uracil-DNA glycosylase, Uncharacterized protein, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | dna mimic protein, dna mimicking, uracil-dna glycosylase inhibitor, uracil-dna glycosylase, hydrolase inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Isoform 1: Mitochondrion. Isoform 2: Nucleus: P13051 |
Total number of polymer chains | 4 |
Total formula weight | 80062.05 |
Authors | Wang, H.C.,Ko, T.P.,Huang, M.F.,Wang, A.H.J. (deposition date: 2015-09-02, release date: 2016-06-08, Last modification date: 2023-11-08) |
Primary citation | Wang, H.C.,Ho, C.H.,Chou, C.C.,Ko, T.P.,Huang, M.F.,Hsu, K.C.,Wang, A.H. Using structural-based protein engineering to modulate the differential inhibition effects of SAUGI on human and HSV uracil DNA glycosylase. Nucleic Acids Res., 44:4440-4449, 2016 Cited by PubMed: 26980279DOI: 10.1093/nar/gkw185 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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