5AXI

Crystal structure of Cbl-b TKB domain in complex with Cblin

Summary for 5AXI

Entry DOI	10.2210/pdb5axi/pdb
Descriptor	E3 ubiquitin-protein ligase CBL-B, Cblin, CALCIUM ION, ... (5 entities in total)
Functional Keywords	ubquitin ligase, phosphopeptide, cblin, ligase-ligase inhibitor complex, ligase/ligase inhibitor
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	4
Total formula weight	108648.26
Authors	Ohno, A.,Maita, N.,Ochi, A.,Nakao, R.,Nikawa, T. (deposition date: 2015-07-29, release date: 2016-03-02, Last modification date: 2023-11-15)
Primary citation	Ohno, A.,Ochi, A.,Maita, N.,Ueji, T.,Bando, A.,Nakao, R.,Hirasaka, K.,Abe, T.,Teshima-Kondo, S.,Nemoto, H.,Okumura, Y.,Higashibata, A.,Yano, S.,Tochio, H.,Nikawa, T. Structural analysis of the TKB domain of ubiquitin ligase Cbl-b complexed with its small inhibitory peptide, Cblin Arch.Biochem.Biophys., 594:1-7, 2016 Cited by PubMed: 26874193 DOI: 10.1016/j.abb.2016.02.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation