5ALW

ligand complex structure of soluble epoxide hydrolase

Summary for 5ALW

Related5AK3 5AK4 5AK5 5AK6 5AKE 5AKG 5AKH 5AKI 5AKJ 5AKK 5AKL 5AKX 5AKY 5AKZ 5ALD 5ALE 5ALF 5ALG 5ALH 5ALI 5ALJ 5ALK 5ALL 5ALM 5ALN 5ALO 5ALP 5ALQ 5ALR 5ALS 5ALT 5ALU 5ALV 5ALX 5ALY 5ALZ 5AM0 5AM1 5AM2 5AM3 5AM4 5AM5
DescriptorBIFUNCTIONAL EPOXIDE HYDROLASE 2, SULFATE ION, DIMETHYL SULFOXIDE, ... (5 entities in total)
Functional Keywordshydrolase
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm P34913
Total number of polymer chains1
Total molecular weight62552.41
Authors
Oster, L.,Tapani, S.,Xue, Y.,Kack, H. (deposition date: 2015-03-08, release date: 2015-05-13, Last modification date: 2018-04-04)
Primary citation
Oster, L.,Tapani, S.,Xue, Y.,Kack, H.
Successful Generation of Structural Information for Fragment-Based Drug Discovery.
Drug Discov Today, 20:1104-, 2015
PubMed: 25931264 (PDB entries with the same primary citation)
DOI: 10.1016/J.DRUDIS.2015.04.005
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25430.2%4.9%3.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution