5AIK

Human DYRK1A in complex with LDN-211898

Summary for 5AIK

• Entry DOI: 10.2210/pdb5aik/pdb
• Related: 5AIL
• Descriptor: DYRK1A DUAL-SPECIFICITY TYROSINE-PHOSPHORYLATION REGULATED KINASE 1A, 4-(7-METHOXY-1-(TRIFLUOROMETHYL)-9H-PYRIDO[3,4-B]INDOL-9-yl)butan-1-amine, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: transferase, dyrk1a, kinase
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 4
• Total formula weight: 180511.82

Authors

Elkins, J.M.,Soundararajan, M.,Muniz, J.R.C.,Cuny, G.,Higgins, J.,Edwards, A.,Bountra, C.,Knapp, S. (deposition date: 2015-02-15, release date: 2015-02-25, Last modification date: 2024-01-10)

• Primary citation: Elkins, J.M.,Soundararajan, M.,Muniz, J.R.C.,Cuny, G.,Higgins, J.,Edwards, A.,Bountra, C.,Knapp, S.; Dyrk1A with Ldn-211898; To be published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)