ligand complex structure of soluble epoxide hydrolase

Summary for 5AIB

Related5AHX 5AI0 5AI4 5AI5 5AI6 5AI8 5AI9 5AIA 5AIC
DescriptorBIFUNCTIONAL EPOXIDE HYDROLASE 2, SULFATE ION, 6-chloro-2H-1,4-benzoxazin-3(4H)-one, ... (4 entities in total)
Functional Keywordshydrolase
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm P34913
Total number of polymer chains1
Total molecular weight62474.49
Oster, L.,Tapani, S.,Xue, Y.,Kack, H. (deposition date: 2015-02-12, release date: 2015-05-13, Last modification date: 2018-04-04)
Primary citation
Oster, L.,Tapani, S.,Xue, Y.,Kack, H.
Successful Generation of Structural Information for Fragment-Based Drug Discovery.
Drug Discov Today, 20:1104-, 2015
PubMed: 25931264 (PDB entries with the same primary citation)
DOI: 10.1016/J.DRUDIS.2015.04.005
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2434 0.4% 4.2% 5.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21