5AHR

Crystal structure of human DNA cross-link repair 1A, crystal form B

Summary for 5AHR

• Entry DOI: 10.2210/pdb5ahr/pdb
• Related: 5AHO
• Descriptor: DNA CROSS-LINK REPAIR 1A PROTEIN, ZINC ION, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: hydrolase, dclre1a, interstrand crosslink repair
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Nucleus : Q6PJP8
• Total number of polymer chains: 1
• Total formula weight: 39009.46

Authors

Allerston, C.K.,Newman, J.A.,Vollmar, M.,Goubin, S.,Forese, D.S.,Chaikuad, A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O. (deposition date: 2015-02-06, release date: 2015-02-18, Last modification date: 2018-01-24)

• Primary citation: Allerston, C.K.,Lee, S.Y.,Newman, J.A.,Schofield, C.J.,Mchugh, P.J.,Gileadi, O.; The Structures of the Snm1A and Snm1B/Apollo Nuclease Domains Reveal a Potential Basis for Their Distinct DNA Processing Activities.; Nucleic Acids Res., 43:11047-, 2015; PubMed: 26582912; DOI: 10.1093/NAR/GKV1256

Experimental method

X-RAY DIFFRACTION (2.19 Å)