5AGY

CRYSTAL STRUCTURE OF A TAU CLASS GST MUTANT FROM GLYCINE

5AGY の概要

• エントリーDOI: 10.2210/pdb5agy/pdb
• 分子名称: GLUTATHIONE S-TRANSFERASE, 4-NITROPHENYL METHANETHIOL, S-(P-NITROBENZYL)GLUTATHIONE, ... (5 entities in total)
• 機能のキーワード: transferase, binding site, catalytic domain, enzyme, induction, detoxification, herbicides, kinetics, site-directed mutagenesis, soy beans, glutathione transferase, protein stability, catalytic mechanism, xenobiotic binding, allosterism
• 由来する生物種: GLYCINE MAX (SOYBEAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 52696.64

構造登録者

Axarli, I.,Muleta, A.W.,Vlachakis, D.,Kossida, S.,Kotzia, G.,Dhavala, P.,Papageorgiou, A.C.,Labrou, N.E. (登録日: 2015-02-04, 公開日: 2015-12-16, 最終更新日: 2024-01-10)

• 主引用文献: Axarli, I.,Muleta, A.W.,Vlachakis, D.,Kossida, S.,Kotzia, G.,Maltezos, A.,Dhavala, P.,Papageorgiou, A.C.,Labrou, N.E.; Directed Evolution of Tau Class Glutathione Transferases Reveals a Site that Regulates Catalytic Efficiency and Masks Cooperativity.; Biochem.J., 473:559-, 2016; PubMed: 26637269; DOI: 10.1042/BJ20150930

実験手法

X-RAY DIFFRACTION (1.75 Å)