5AES

Crystal Structure of murine Chronophin (Pyridoxal Phosphate Phosphatase) in Complex with a PNP-derived Inhibitor

5AES の概要

• エントリーDOI: 10.2210/pdb5aes/pdb
• 分子名称: PYRIDOXAL PHOSPHATE PHOSPHATASE, MAGNESIUM ION, {2-[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]ethyl}phosphonic acid, ... (5 entities in total)
• 機能のキーワード: hydrolase, pdxp, plpp, haloacid dehalogenase, had phosphatase, had hydrolase
• 由来する生物種: MUS MUSCULUS (HOUSE MOUSE)
• 細胞内の位置: Cytoplasm, cytosol : P60487
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 63864.93

構造登録者

Knobloch, G.,Jabari, N.,Koehn, M.,Gohla, A.,Schindelin, H. (登録日: 2015-01-09, 公開日: 2015-04-01, 最終更新日: 2024-01-10)

• 主引用文献: Knobloch, G.,Jabari, N.,Stadlbauer, S.,Schindelin, H.,Kohn, M.,Gohla, A.; Synthesis of Hydrolysis-Resistant Pyridoxal 5'-Phosphate Analogs and Their Biochemical and X-Ray Crystallographic Characterization with the Pyridoxal Phosphatase Chronophin.; Bioorg.Med.Chem., 23:2819-, 2015; PubMed: 25783190; DOI: 10.1016/J.BMC.2015.02.049

実験手法

X-RAY DIFFRACTION (2.751 Å)