5AEN

Structure of human Leukotriene A4 hydrolase in complex with inhibitor dimethyl(2- (4-phenoxyphenoxy)ethyl)amine

5AEN の概要

• エントリーDOI: 10.2210/pdb5aen/pdb
• 分子名称: LEUKOTRIENE A-4 HYDROLASE, N,N-dimethyl-2-(4-phenoxyphenoxy)ethanamine, ZINC ION, ... (6 entities in total)
• 機能のキーワード: hydrolase, leukotriene (lt) a4 hydrolase/aminopeptidase, lta4h
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 70159.61

構造登録者

Moser, D.,Wittmann, S.K.,Kramer, J.,Blocher, R.,Achenbach, J.,Pogoryelov, D.,Proschak, E. (登録日: 2015-01-06, 公開日: 2015-02-11, 最終更新日: 2024-01-10)

• 主引用文献: Moser, D.,Wittmann, S.K.,Kramer, J.,Blocher, R.,Achenbach, J.,Pogoryelov, D.,Proschak, E.; Peng: A Neural Gas-Based Approach for Pharmacophore Elucidation. Method Design, Validation and Virtual Screening for Novel Ligands of Lta4H.; J.Chem.Inf.Model., 55:284-, 2015; PubMed: 25625859; DOI: 10.1021/CI500618U

実験手法