5ACT

W228S-Investigation of the impact from residues W228 and Y233 in the metallo-beta-lactamase GIM-1

Summary for 5ACT

Entry DOI	10.2210/pdb5act/pdb
Related	5ACP 5ACQ 5ACR 5ACS
Descriptor	GIM-1 PROTEIN, ZINC ION (3 entities in total)
Functional Keywords	hydrolase, metallo-beta-lactamase, gim-1, carbapenemase, enzyme kinetics, mic
Biological source	PSEUDOMONAS AERUGINOSA
Total number of polymer chains	2
Total formula weight	54936.91
Authors	Skagseth, S.,Carlsen, T.J.,Bjerga, G.E.K.,Spencer, J.,Samuelsen, O.,Leiros, H.-K.S. (deposition date: 2015-08-17, release date: 2015-12-23, Last modification date: 2024-01-10)
Primary citation	Skagseth, S.,Carlsen, T.J.,Bjerga, G.E.K.,Spencer, J.,Samuelsen, O.,Leiros, H.S. Role of Residues W228 and Y233 in the Structure and Activity of Metallo-Beta-Lactamase Gim-1. Antimicrob.Agents Chemother., 60:990-, 2015 Cited by PubMed: 26643332 DOI: 10.1128/AAC.02017-15 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.81 Å)

Structure validation