5A6N

Crystal structure of human death associated protein kinase 3 (DAPK3) in complex with compound 2

Summary for 5A6N

• Entry DOI: 10.2210/pdb5a6n/pdb
• Related: 5A6O
• Descriptor: DEATH-ASSOCIATED PROTEIN KINASE 3, 5-(3-SULFAMOYLPHENYL)-1H-1,2,3,4-TETRAZOL-1-IDE, GLYCEROL, ... (5 entities in total)
• Functional Keywords: transferase, dapk3, human death associated protein kinase 3, dap-like kinase, dlk, zipper-interacting protein kinase, zip-kinase
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Nucleus . Isoform 1: Nucleus . Isoform 2: Nucleus : O43293
• Total number of polymer chains: 2
• Total formula weight: 65651.85

Authors

Rodrigues, T.,Reker, D.,Welin, M.,Caldera, M.,Brunner, C.,Gabernet, G.,Schneider, P.,Walse, B.,Schneider, G. (deposition date: 2015-06-30, release date: 2015-10-21, Last modification date: 2024-01-10)

• Primary citation: Rodrigues, T.,Reker, D.,Welin, M.,Caldera, M.,Brunner, C.,Gabernet, G.,Schneider, P.,Walse, B.,Schneider, G.; De Novo Fragment Design for Drug Discovery and Chemical Biology.; Angew.Chem.Int.Ed.Engl., 54:15079-, 2015; PubMed: 26486226; DOI: 10.1002/ANIE.201508055

Experimental method

X-RAY DIFFRACTION (1.7 Å)