5A6K
GH20C, Beta-hexosaminidase from Streptococcus pneumoniae in complex with Gal-NGT
Summary for 5A6K
| Entry DOI | 10.2210/pdb5a6k/pdb |
| Related | 5A69 5A6A 5A6B 5A6J |
| Descriptor | GH20C, (2S,3aR,5R,6R,7R,7aR)-5-(hydroxymethyl)-2-methyl-2,3a,5,6,7,7a-hexahydro-1H-pyrano[3,2-d][1,3]thiazole-6,7-diol (3 entities in total) |
| Functional Keywords | beta-hexosaminidase, streptococcus pneumoniae, bacterial proteins, carbohydrate conformation, catalytic domain, enzyme inhibitors, host-pathogen interactions, hydrogen bonding, hydrolysis, models, polysaccharides, protein binding, virulence factors, hydrolase |
| Biological source | STREPTOCOCCUS PNEUMONIAE |
| Total number of polymer chains | 2 |
| Total formula weight | 148805.58 |
| Authors | Cid, M.,Robb, C.S.,Higgins, M.A.,Boraston, A.B. (deposition date: 2015-06-26, release date: 2015-09-23, Last modification date: 2024-01-10) |
| Primary citation | Robb, M.,Robb, C.S.,Higgins, M.A.,Hobbs, J.K.,Paton, J.C.,Boraston, A.B. A Second Beta-Hexosaminidase Encoded in the Streptococcus Pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans J.Biol.Chem., 290:30888-, 2015 Cited by PubMed: 26491009DOI: 10.1074/JBC.M115.688630 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report
