5A4Q

DYRK1A IN COMPLEX WITH CHLORO BENZOTHIAZOLE FRAGMENT

Summary for 5A4Q

Entry DOI	10.2210/pdb5a4q/pdb
Related	5A4E 5A4L 5A4T 5A54
Descriptor	DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1A, N-(5-CHLORANYL-1,3-BENZOTHIAZOL-2-YL)ETHANAMIDE (3 entities in total)
Functional Keywords	transferase
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	4
Total formula weight	171522.70
Authors	Rothweiler, U. (deposition date: 2015-06-11, release date: 2016-06-29, Last modification date: 2024-01-10)
Primary citation	Rothweiler, U.,Stensen, W.,Brandsdal, B.O.,Isaksson, J.,Leeson, F.A.,Eugh, R.A.,Mjoen Svendsen, J.S. Probing the ATP-Binding Pocket of Protein Kinase Dyrk1A with Benzothiazole Fragment Molecules J.Med.Chem., 59:9814-, 2016 Cited by PubMed: 27736065 DOI: 10.1021/ACS.JMEDCHEM.6B01086 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.37 Å)

Structure validation