5A1I
The structure of Human MAT2A in complex with SAM, Adenosine, Methionine and PPNP.
Summary for 5A1I
| Entry DOI | 10.2210/pdb5a1i/pdb |
| Related | 5A19 5A1G |
| Descriptor | S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2, TETRAETHYLENE GLYCOL, METHIONINE, ... (11 entities in total) |
| Functional Keywords | transferase, methionine adenosyltransferase, cell growth, liver cancer, methylation |
| Biological source | HOMO SAPIENS (HUMAN) |
| Total number of polymer chains | 1 |
| Total formula weight | 45281.70 |
| Authors | Murray, B.,Antonyuk, S.V.,Marina, A.,Lu, S.C.,Mato, J.M.,Hasnain, S.S.,Rojas, A.L. (deposition date: 2015-04-30, release date: 2016-03-09, Last modification date: 2024-01-10) |
| Primary citation | Murray, B.,Antonyuk, S.V.,Marina, A.,Lu, S.C.,Mato, J.M.,Hasnain, S.S.,Rojas, A.L. Crystallography Captures Catalytic Steps in Human Methionine Adenosyltransferase Enzymes. Proc.Natl.Acad.Sci.USA, 113:2104-, 2016 Cited by PubMed: 26858410DOI: 10.1073/PNAS.1510959113 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.09 Å) |
Structure validation
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