5A1I
The structure of Human MAT2A in complex with SAM, Adenosine, Methionine and PPNP.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2 | polymer | 395 | 43720.6 | 1 | UniProt (P31153) Pfam (PF00438) Pfam (PF02772) Pfam (PF02773) | HOMO SAPIENS (HUMAN) | ADOMET SYNTHASE 2, METHIONINE ADENOSYLTRANSFERASE 2, MAT 2, METHIONINE ADENOSYLTRANSFERASE II, MAT-II, METHIONINE ADENOSYLTRANSFERASE 2A |
| 2 | B (A) | METHIONINE | non-polymer | 149.2 | 1 | Chemie (MET) PubChem (876) PubChem (6137) PubChem (84815) | |||
| 3 | C (A) | (DIPHOSPHONO)AMINOPHOSPHONIC ACID | non-polymer | 257.0 | 1 | Chemie (PPK) PubChem (447781) | |||
| 4 | D, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 5 | F, G (A) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) PubChem (813) | |||
| 6 | H (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) PubChem (5136) PubChem (34755) PubChem (58633578) PubChem (60038769) PubChem (58766358) PubChem (73897310) PubChem (9865603) PubChem (87224684) PubChem (12312798) PubChem (131697735) PubChem (145712080) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) | |||
| 7 | I (A) | ADENOSINE | non-polymer | 267.2 | 1 | Chemie (ADN) | |||
| 8 | J (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 9 | K (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 10 | L (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) PubChem (8200) | |||
| 11 | M (A) | water | water | 18.0 | 515 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43720.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1561.1 | |
| All* | Total formula weight | 45281.7 |
