5A1I
The structure of Human MAT2A in complex with SAM, Adenosine, Methionine and PPNP.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2 | polymer | 395 | 43720.6 | 1 | UniProt (P31153) Pfam (PF00438) Pfam (PF02772) Pfam (PF02773) | HOMO SAPIENS (HUMAN) | ADOMET SYNTHASE 2, METHIONINE ADENOSYLTRANSFERASE 2, MAT 2, METHIONINE ADENOSYLTRANSFERASE II, MAT-II, METHIONINE ADENOSYLTRANSFERASE 2A |
| 2 | B (A) | METHIONINE | non-polymer | 149.2 | 1 | Chemie (MET) | |||
| 3 | C (A) | (DIPHOSPHONO)AMINOPHOSPHONIC ACID | non-polymer | 257.0 | 1 | Chemie (PPK) | |||
| 4 | D, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | F, G (A) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 6 | H (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 7 | I (A) | ADENOSINE | non-polymer | 267.2 | 1 | Chemie (ADN) | |||
| 8 | J (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 9 | K (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 10 | L (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 11 | M (A) | water | water | 18.0 | 515 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43720.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1561.1 | |
| All* | Total formula weight | 45281.7 |
