5A1F

Crystal structure of the catalytic domain of PLU1 in complex with N-oxalylglycine.

5A1F の概要

• エントリーDOI: 10.2210/pdb5a1f/pdb
• 分子名称: LYSINE-SPECIFIC DEMETHYLASE 5B, LYSINE-SPECIFIC DEMETHYLASE 5B, ZINC ION, N-OXALYLGLYCINE, ... (8 entities in total)
• 機能のキーワード: oxidoreductase, lysine-specific demethylase 5b
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Nucleus : Q9UGL1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 56141.63

構造登録者

Srikannathasan, V.,Johansson, C.,Strain-Damerell, C.,Gileadi, C.,Szykowska, A.,Kupinska, K.,Kopec, J.,Krojer, T.,Steuber, H.,von Delft, F.,Burgess-Brown, N.A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Oppermann, U. (登録日: 2015-04-29, 公開日: 2015-05-06, 最終更新日: 2024-01-10)

• 主引用文献: Johansson, C.,Velupillai, S.,Tumber, A.,Szykowska, A.,Hookway, E.S.,Nowak, R.P.,Strain-Damerell, C.,Gileadi, C.,Philpott, M.,Burgess-Brown, N.,Wu, N.,Kopec, J.,Nuzzi, A.,Steuber, H.,Egner, U.,Badock, V.,Munro, S.,Lathangue, N.B.,Westaway, S.,Brown, J.,Athanasou, N.,Prinjha, R.,Brennan, P.E.,Oppermann, U.; Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development.; Nat.Chem.Biol., 12:539-, 2016; PubMed: 27214403; DOI: 10.1038/NCHEMBIO.2087

実験手法

X-RAY DIFFRACTION (2.1 Å)