5ZTO
Crystal structure of EGFR 696-1022 T790M/C797S in complex with D3003
Summary for 5ZTO
Entry DOI | 10.2210/pdb5zto/pdb |
Descriptor | Epidermal growth factor receptor, N-{trans-4-[3-(2-chlorophenyl)-7-{[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]cyclohexyl}propanamide, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | egfr, t790m/c797s, inhibitor, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 38287.17 |
Authors | |
Primary citation | Zhu, S.J.,Yun, C.H. Crystal structure of EGFR 696-1022 T790M/C797S in complex with D3003 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.649 Å) |
Structure validation
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