5YZI
Crystal Structure of Mouse Cytosolic Isocitrate Dehydrogenase complexed with Cadmium
Replaces: 2CMVSummary for 5YZI
Entry DOI | 10.2210/pdb5yzi/pdb |
Descriptor | Isocitrate dehydrogenase [NADP] cytoplasmic, CADMIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total) |
Functional Keywords | idh, oxidoreductase |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 2 |
Total formula weight | 95296.84 |
Authors | Cho, H.J.,Kang, B.S. (deposition date: 2017-12-14, release date: 2018-07-04, Last modification date: 2024-03-27) |
Primary citation | Cho, H.J.,Cho, H.Y.,Park, J.W.,Kwon, O.S.,Lee, H.S.,Huh, T.L.,Kang, B.S. NADP+-dependent cytosolic isocitrate dehydrogenase provides NADPH in the presence of cadmium due to the moderate chelating effect of glutathione. J. Biol. Inorg. Chem., 23:849-860, 2018 Cited by PubMed: 29923039DOI: 10.1007/s00775-018-1581-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.519 Å) |
Structure validation
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