5YZ3
Crystal structure of T2R-TTL-28 complex
Summary for 5YZ3
Entry DOI | 10.2210/pdb5yz3/pdb |
Descriptor | Tubulin alpha-1B chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, N-[4-(diethylamino)phenyl]-4H-pyrrolo[2,3-d][1,3]thiazole-5-carboxamide, ... (15 entities in total) |
Functional Keywords | tubulin, complex, structural protein-inhibitor complex, structural protein, cell cycle |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 6 |
Total formula weight | 264974.89 |
Authors | |
Primary citation | Ning, N.,Yu, Y.,Wu, M.,Zhang, R.,Zhang, T.,Zhu, C.,Huang, L.,Yun, C.H.,Benes, C.H.,Zhang, J.,Deng, X.,Chen, Q.,Ren, R. A Novel Microtubule Inhibitor Overcomes Multidrug Resistance in Tumors. Cancer Res., 78:5949-5957, 2018 Cited by PubMed: 30135190DOI: 10.1158/0008-5472.CAN-18-0455 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.545 Å) |
Structure validation
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