5YJ8
Identification of a small molecule inhibitor for the Tudor domain of TDRD3
Summary for 5YJ8
Entry DOI | 10.2210/pdb5yj8/pdb |
Descriptor | Tudor domain-containing protein 3, 5-(aminomethyl)-1,3-dimethyl-benzimidazol-2-one, SULFATE ION, ... (4 entities in total) |
Functional Keywords | transcriptional coactivator, complex, inhibitor, transcription-inhibitor complex, transcription/inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 7434.38 |
Authors | |
Primary citation | Liu, J.,Zhang, S.,Liu, M.,Liu, Y.,Nshogoza, G.,Gao, J.,Ma, R.,Yang, Y.,Wu, J.,Zhang, J.,Li, F.,Ruan, K. Structural plasticity of the TDRD3 Tudor domain probed by a fragment screening hit. FEBS J., 285:2091-2103, 2018 Cited by PubMed: 29645362DOI: 10.1111/febs.14469 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.762 Å) |
Structure validation
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