5XRE

Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor JX1

Summary for 5XRE

• Entry DOI: 10.2210/pdb5xre/pdb
• Descriptor: Heat shock protein HSP 90-alpha, N-[4-(4-methoxyphenyl)-3-[5-(8-methylquinolin-5-yl)-2,4-bis(oxidanyl)phenyl]-1,2-oxazol-5-yl]ethanamide (3 entities in total)
• Functional Keywords: heat shock protein hsp 90, chaperone
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 26138.27

Authors

Li, J.,Shi, F.,Xiong, B.,He, J.H. (deposition date: 2017-06-08, release date: 2018-07-04, Last modification date: 2024-03-27)

• Primary citation: Li, J.,Shi, F.,Xiong, B.,He, J.H.; Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor JX1; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.497 Å)