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5XRE

Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor JX1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AHeat shock protein HSP 90-alphapolymer22825656.81UniProt (P07900)
Pfam (PF13589)
In PDB
Homo sapiens (Human)Heat shock 86 kDa,HSP86,Lipopolysaccharide-associated protein 2,LPS-associated protein 2,Renal carcinoma antigen NY-REN-38
2AN-[4-(4-methoxyphenyl)-3-[5-(8-methylquinolin-5-yl)-2,4-bis(oxidanyl)phenyl]-1,2-oxazol-5-yl]ethanamidenon-polymer481.51Chemie (JX1)
3waterwater18.0264Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight25656.8
Non-Polymers*Number of molecules1
Total formula weight481.5
All*Total formula weight26138.3
*Water molecules are not included.

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PDB entries from 2024-09-04

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