5XN2
HIV-1 reverse transcriptase Q151M:DNA:dGTP ternary complex
Summary for 5XN2
Entry DOI | 10.2210/pdb5xn2/pdb |
Related | 4ZHR |
Related PRD ID | PRD_900003 |
Descriptor | Pol protein, 38-MER DNA aptamer, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | hiv-1, hbv, reverse transcriptase, drug resistance, drug sensitivity, entecavir, transferase-dna complex, transferase/dna |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 6 |
Total formula weight | 257012.52 |
Authors | Yasutake, Y.,Tamura, N.,Hayashi, H.,Maeda, K. (deposition date: 2017-05-17, release date: 2018-02-07, Last modification date: 2023-11-22) |
Primary citation | Yasutake, Y.,Hattori, S.I.,Hayashi, H.,Matsuda, K.,Tamura, N.,Kohgo, S.,Maeda, K.,Mitsuya, H. HIV-1 with HBV-associated Q151M substitution in RT becomes highly susceptible to entecavir: structural insights into HBV-RT inhibition by entecavir. Sci Rep, 8:1624-1624, 2018 Cited by PubMed: 29374261DOI: 10.1038/s41598-018-19602-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.381 Å) |
Structure validation
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