5XN2
HIV-1 reverse transcriptase Q151M:DNA:dGTP ternary complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Pol protein | polymer | 557 | 64033.4 | 2 | UniProt (D3XFN7) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) UniProt (by SIFTS) (P12497) In PDB | Human immunodeficiency virus 1 | |
2 | B, D | Pol protein | polymer | 444 | 51861.5 | 2 | UniProt (D3XFN7) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) UniProt (by SIFTS) (P12497) In PDB | Human immunodeficiency virus 1 | HIV-1 reverse transcriptase p51 subunit |
3 | E, F | 38-MER DNA aptamer | polymer | 38 | 11724.5 | 2 | synthetic construct | ||
4 | G | beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900003) | sucrose | ||
5 | A, C | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
6 | A, C | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (DGT) | |||
7 | A, B, D | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
8 | water | water | 18.0 | 321 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 555 (UniProt: D3XFN7)
B, D: 1 - 428 (UniProt: D3XFN7)
PDB | External Database | Details |
---|---|---|
Met -1 | - | expression tag |
Val 0 | - | expression tag |
Met 151 | Gln 250 | engineered mutation |
Ser 162 | Cys 261 | engineered mutation |
Ser 280 | Cys 379 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Met -15 | - | expression tag |
Ala -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
Ala -7 | - | expression tag |
Leu -6 | - | expression tag |
Glu -5 | - | expression tag |
Val -4 | - | expression tag |
Leu -3 | - | expression tag |
Phe -2 | - | expression tag |
Gln -1 | - | expression tag |
Gly 0 | - | expression tag |
Ser 162 | Cys 261 | engineered mutation |
Ser 280 | Cys 379 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 255238.9 | |
Branched | Number of molecules | 1 |
Total formula weight | 342.3 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1431.3 | |
All* | Total formula weight | 257012.5 |