5XI7
Crystal structure of T2R-TTL bound with PO-7
Summary for 5XI7
Entry DOI | 10.2210/pdb5xi7/pdb |
Descriptor | Tubulin alpha chain, (6Z)-3-[[2,5-bis(fluoranyl)phenyl]methylidene]-6-[(4-tert-butyl-1H-imidazol-5-yl)methylidene]piperazine-2,5-dione, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (12 entities in total) |
Functional Keywords | tubulin, microtubule, colchicine, stathmin, structural protein |
Biological source | Rattus norvegicus (Rat) More |
Cellular location | Cytoplasm, cytoskeleton : A0A0R4I993 A0A0R4I995 Golgi apparatus : P63043 |
Total number of polymer chains | 6 |
Total formula weight | 269969.12 |
Authors | |
Primary citation | Chu, Y.,Wang, Y.,Yang, J.,Li, W. Synthesis, biological evaluation and X-ray structure of anti-microtubule agents To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.99 Å) |
Structure validation
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