5WNZ
DNA polymerase beta substrate complex with incoming 5-FodCTP
Summary for 5WNZ
Entry DOI | 10.2210/pdb5wnz/pdb |
Descriptor | DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... (9 entities in total) |
Functional Keywords | dna ligase/dna, transferase, dna ligase-dna, transferase complex |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 48364.62 |
Authors | Schaich, M.A.,Smith, M.R.,Cloud, A.S.,Holloran, S.M.,Freudenthal, B.D. (deposition date: 2017-08-01, release date: 2017-09-13, Last modification date: 2023-10-04) |
Primary citation | Schaich, M.A.,Smith, M.R.,Cloud, A.S.,Holloran, S.M.,Freudenthal, B.D. Structures of a DNA Polymerase Inserting Therapeutic Nucleotide Analogues. Chem. Res. Toxicol., 30:1993-2001, 2017 Cited by PubMed: 28862449DOI: 10.1021/acs.chemrestox.7b00173 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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