5WNK
Crystal structure of murine receptor-interacting protein 4 (Ripk4) D143N bound to TG100-115
Summary for 5WNK
| Entry DOI | 10.2210/pdb5wnk/pdb |
| Related | 5WNI 5WNJ 5WNL 5WNM |
| Descriptor | Receptor-interacting serine/threonine-protein kinase 4, CHLORIDE ION, 3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol, ... (4 entities in total) |
| Functional Keywords | kinase, inhibitor, complex, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Mus musculus (Mouse) |
| Cellular location | Cytoplasm: Q9ERK0 |
| Total number of polymer chains | 1 |
| Total formula weight | 39369.83 |
| Authors | Huang, C.S.,Hymowitz, S.G. (deposition date: 2017-08-01, release date: 2018-05-09, Last modification date: 2024-03-13) |
| Primary citation | Huang, C.S.,Oberbeck, N.,Hsiao, Y.C.,Liu, P.,Johnson, A.R.,Dixit, V.M.,Hymowitz, S.G. Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity. Structure, 26:767-, 2018 Cited by PubMed: 29706531DOI: 10.1016/j.str.2018.04.002 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.11 Å) |
Structure validation
Download full validation report
