5W5L
Crystal structure of human IgG1-Sigma Fc fragment
Summary for 5W5L
Entry DOI | 10.2210/pdb5w5l/pdb |
Descriptor | Immunoglobulin gamma-1 heavy chain, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | fc, immunoglobulin fold, immune system |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 53163.29 |
Authors | Armstrong, A.A.,Gilliland, G.L. (deposition date: 2017-06-15, release date: 2017-09-13, Last modification date: 2023-10-04) |
Primary citation | Tam, S.H.,McCarthy, S.G.,Armstrong, A.A.,Somani, S.,Wu, S.J.,Liu, X.,Gervais, A.,Ernst, R.,Saro, D.,Decker, R.,Luo, J.,Gilliland, G.L.,Chiu, M.L.,Scallon, B.J. Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality. Antibodies, 6:-, 2017 Cited by PubMed: 31548527DOI: 10.3390/antib6030012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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