5W5L
Crystal structure of human IgG1-Sigma Fc fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Immunoglobulin gamma-1 heavy chain | polymer | 223 | 24956.2 | 2 | UniProt (P0DOX5) Pfam (PF07654) In PDB | Homo sapiens (Human) | Immunoglobulin gamma-1 heavy chain NIE |
| 2 | C, D | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1625.5 | 2 | In PDB GlyTouCan (G27919IH) | |||
| 3 | water | water | 18.0 | 260 | Chemie (HOH) |
Sequence modifications
A, B: 225 - 447 (UniProt: P0DOX5)
| PDB | External Database | Details |
|---|---|---|
| Ala 234 | Leu 236 | engineered mutation |
| Ala 235 | Leu 237 | engineered mutation |
| Ala 237 | Gly 239 | engineered mutation |
| Ser 238 | Pro 240 | engineered mutation |
| Ala 268 | His 270 | engineered mutation |
| Ser 330 | Ala 332 | engineered mutation |
| Ser 331 | Pro 333 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49912.3 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 3251.0 | |
| All* | Total formula weight | 53163.3 |
