5W06

HUMAN TISSUE FACTOR IN COMPLEX WITH ANTIBODY M1587

Summary for 5W06

• Entry DOI: 10.2210/pdb5w06/pdb
• Related: 4m7k 4m7l 5W06
• Descriptor: Tissue factor, M1587 FAB LIGHT CHAIN, M1587 FAB HEAVY CHAIN, ... (5 entities in total)
• Functional Keywords: immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Isoform 1: Membrane ; Single-pass type I membrane protein . Isoform 2: Secreted : P13726
• Total number of polymer chains: 3
• Total formula weight: 73396.75

Authors

Teplyakov, A.,Obmolova, G.,Malia, T.J.,Gilliland, G.L. (deposition date: 2017-05-30, release date: 2017-06-14, Last modification date: 2023-10-04)

• Primary citation: Teplyakov, A.,Obmolova, G.,Malia, T.J.,Raghunathan, G.,Martinez, C.,Fransson, J.,Edwards, W.,Connor, J.,Husovsky, M.,Beck, H.,Chi, E.,Fenton, S.,Zhou, H.,Almagro, J.C.,Gilliland, G.L.; Structural insights into humanization of anti-tissue factor antibody 10H10.; MAbs, 10:269-277, 2018; PubMed: 29283291; DOI: 10.1080/19420862.2017.1412026

Experimental method

X-RAY DIFFRACTION (2.6 Å)