5VB3
X-ray structure of nuclear receptor ROR-gammat Ligand Binding Domain + SRC2 peptide
Summary for 5VB3
Entry DOI | 10.2210/pdb5vb3/pdb |
Related | 5VB5 5VB6 5VB7 |
Descriptor | Nuclear receptor ROR-gamma, SRC2 chimera, SODIUM ION (3 entities in total) |
Functional Keywords | nuclear receptor, nuclear hormone receptor, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 32465.43 |
Authors | |
Primary citation | Li, X.,Anderson, M.,Collin, D.,Muegge, I.,Wan, J.,Brennan, D.,Kugler, S.,Terenzio, D.,Kennedy, C.,Lin, S.,Labadia, M.E.,Cook, B.,Hughes, R.,Farrow, N.A. Structural studies unravel the active conformation of apo ROR gamma t nuclear receptor and a common inverse agonism of two diverse classes of ROR gamma t inhibitors. J. Biol. Chem., 292:11618-11630, 2017 Cited by PubMed: 28546429DOI: 10.1074/jbc.M117.789024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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