5VAQ
Crystal Structure of Beta-Klotho in Complex with FGF21CT
Summary for 5VAQ
Entry DOI | 10.2210/pdb5vaq/pdb |
Related | 5V9Q 5V9R |
Descriptor | Beta-klotho, Nb914, Fibroblast growth factor 21, ... (4 entities in total) |
Functional Keywords | (beta/alpha) 8 receptor for endocrine fgf, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 127050.57 |
Authors | Lee, S.,Schlessinger, J. (deposition date: 2017-03-27, release date: 2018-01-31, Last modification date: 2021-03-24) |
Primary citation | Lee, S.,Choi, J.,Mohanty, J.,Sousa, L.P.,Tome, F.,Pardon, E.,Steyaert, J.,Lemmon, M.A.,Lax, I.,Schlessinger, J. Structures of beta-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling. Nature, 553:501-505, 2018 Cited by PubMed: 29342135DOI: 10.1038/nature25010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.606 Å) |
Structure validation
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